Shredder
Shredder is a research-grade liquid formulation combining L-Carnitine, MIC blend (Methionine, Inositol, Choline), ATP, Albuterol, and B12 (Methylcobalamin). Preclinical studies on the individual components suggest complementary roles in fatty acid oxidation, energy metabolism, lipolysis, and metabolic support. In animal and in vitro models, these compounds have been investigated for their potential synergistic effects on lipid handling, thermogenesis, and cellular energy pathways.[1][2]
Key Research Areas
- Fatty Acid Oxidation & Lipolysis – In rodent models of obesity and metabolic challenge, L-Carnitine facilitates mitochondrial β-oxidation, while Albuterol (a β2-adrenergic agonist) promotes lipolysis and energy expenditure in adipose tissue.[3][4]
- Lipid Metabolism & Methylation Support – The MIC blend (Methionine, Inositol, Choline) supports phospholipid synthesis, prevents hepatic lipid accumulation, and aids in one-carbon metabolism in preclinical high-fat diet models.[5][6]
- Energy Production & Cellular Support – ATP provides direct cellular energy substrate, and B12 contributes to mitochondrial function and methylation in models of metabolic stress and fatigue.[7][8]
Product Specifications
| Form |
Ready-to-use liquid solution |
| Composition per mL |
L-Carnitine: 400 mg
MIC Blend: 100 mg
ATP: 50 mg
Albuterol: 2 mg
B12 (Methylcobalamin): 1 mg |
| Synonyms |
Shredder Liquid Blend, Lipo-MIC + Albuterol + ATP Research Solution |
| Storage |
2–8°C (refrigerated), protect from light |
| Solubility / Vehicle |
Pre-dissolved in research-grade solvent system (e.g., compatible with DMSO or aqueous base) |
References
- 1. Rebouche CJ. Carnitine function and requirements during the life cycle. FASEB J. 1992. PubMed
- 2. Zeisel SH, et al. Choline: an essential nutrient for public health. Nutr Rev. 2009. PubMed
- 3. Kerner J, et al. Carnitine palmitoyltransferase I and regulation of mitochondrial fatty acid oxidation. Biochim Biophys Acta. 1995. PubMed
- 4. Lafontan M, et al. Beta-adrenergic regulation of lipolysis and lipid mobilization in humans. Am J Physiol. 1993. PubMed
- 5. Corbin KD, et al. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol. 2012. PubMed
- 6. Finkelstein JD. Methionine metabolism in mammals. J Nutr Biochem. 1990. PubMed
- 7. Burnstock G. Purinergic signalling: Its unpopular beginning, its acceptance and its exciting future. Bioessays. 2012. (ATP signaling context)
- 8. Kennedy EP. The biosynthesis of phospholipids. J Lipid Res. 1957. (B12/methylation context)
All products offered by Premier Research are intended for laboratory research use only. These materials are not for human or veterinary consumption, medical use, diagnostic procedures, or therapeutic applications. Statements on this website are for informational and educational purposes only and have not been evaluated by the U.S. Food and Drug Administration (FDA). By accessing this site, you confirm that you are a qualified researcher or institution representative and agree to use all materials in accordance with applicable laws, regulations, and safety guidelines.
