LIPO-B (MIC + B-Complex)
LIPO-B is a research-grade liquid formulation combining L-Carnitine, L-Arginine, L-Methionine, Inositol, Choline, and B-vitamins (B5, B6, B12). Preclinical studies on the individual components suggest complementary roles in fatty acid metabolism, methylation support, and energy production pathways. In animal and in vitro models, these compounds have been investigated for their potential synergistic effects on lipid handling, liver function, and metabolic regulation.[1][2]
Key Research Areas
- Lipid Metabolism & Fatty Acid Transport – In rodent models, L-Carnitine facilitates mitochondrial β-oxidation, while Choline and Inositol support phospholipid synthesis and prevent fatty liver accumulation.[3][4]
- Methylation & Detoxification Pathways – L-Methionine and B-vitamins contribute to one-carbon metabolism, homocysteine remethylation, and glutathione synthesis in preclinical metabolic stress models.[5][6]
- Energy Production & Cellular Support – In vitro and animal studies indicate L-Arginine, B-complex vitamins, and related compounds enhance nitric oxide signaling, ATP generation, and overall metabolic homeostasis.[7][8]
Product Specifications
| Form |
Ready-to-use liquid solution (dissolved in DMSO or compatible vehicle) |
| Composition per mL |
L-Carnitine: 20 mg
L-Arginine: 20 mg
L-Methionine: 25 mg
Inositol: 50 mg
Choline: 50 mg
B6 (Pyridoxine): 25 mg
B5 (Dexpanthenol): 25 mg
B12 (Methylcobalamin): 1 mg |
| Synonyms |
LIPO-B MIC + B-Complex, Lipotropic Blend, Fat Metabolism Research Solution |
| Storage |
Room temp or 2–8°C (refrigerated), protect from light |
| Solubility / Vehicle |
Pre-dissolved in DMSO or research-grade solvent system |
References
- 1. Rebouche CJ. Carnitine function and requirements during the life cycle. FASEB J. 1992. PubMed
- 2. Zeisel SH, et al. Choline: an essential nutrient for public health. Nutr Rev. 2009. PubMed
- 3. Kerner J, et al. Carnitine palmitoyltransferase I and regulation of mitochondrial fatty acid oxidation. Biochim Biophys Acta. 1995. PubMed
- 4. Corbin KD, et al. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol. 2012. PubMed
- 5. Finkelstein JD. Methionine metabolism in mammals. J Nutr Biochem. 1990. PubMed
- 6. Selhub J. Homocysteine metabolism. Annu Rev Nutr. 1999. PubMed
- 7. Wu G, et al. Arginine metabolism: nitric oxide and beyond. Biochem J. 1998. PubMed
- 8. Combs GF Jr. The vitamins: fundamental aspects in nutrition and health. Academic Press. 2012. (B-vitamin metabolic roles)
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