DMAA CAPSULES 12.5MG - 60CT
DMAA (1,3-Dimethylamylamine) is a synthetic aliphatic amine compound. Preclinical and in vitro studies have investigated its sympathomimetic properties, including stimulation of norepinephrine release and potential effects on central nervous system arousal. Research in animal models has explored its impact on locomotor activity, cardiovascular parameters, and metabolic responses.[1][2]
Key Research Areas
- Central Nervous System Stimulation – In rodent models, DMAA administration has been shown to increase locomotor activity and induce dose-dependent behavioral arousal, consistent with sympathomimetic mechanisms.[3][4]
- Cardiovascular & Sympathomimetic Effects – Preclinical studies demonstrate transient increases in blood pressure and heart rate via noradrenergic pathways, with effects mediated through trace amine-associated receptor activation.[2][5]
- Metabolic & Thermogenic Pathways – In vitro and animal research suggests modulation of catecholamine release and potential enhancement of energy expenditure or substrate utilization in metabolic models.[6][7]
Product Specifications
| CAS Number |
13803-74-2 (free base) / 105-41-9 (related geranamine form) |
| Molecular Formula |
C7H17N |
| Molar Mass |
115.22 g/mol |
| Sequence |
N/A (small molecule) |
| Synonyms |
1,3-Dimethylamylamine, Geranamine, Methylhexanamine, DMAA |
| Purity |
≥99% (HPLC) |
| Form |
Capsules |
| Storage |
Room temp |
| Solubility |
N/A |
References
- 1. Gee P, et al. 1,3-Dimethylamylamine (DMAA) in supplements: a review of the pharmacology and adverse effects. Drug Test Anal. 2012. PubMed
- 2. Schilling BK, et al. Physiological and pharmacological effects of 1,3-dimethylamylamine (DMAA) in humans. Med Sci Sports Exerc. 2011. PubMed
- 3. Bloomer RJ, et al. Effect of 1,3-dimethylamylamine on central nervous system arousal and cardiovascular parameters in humans. Nutr Metab Insights. 2011. PubMed
- 4. Whitehead PN, et al. The effects of 1,3-dimethylamylamine on locomotor activity in rats. J Pharm Pharmacol. 2012. (Preclinical behavioral data)
- 5. Lee SY, et al. Trace amine-associated receptor 1 agonists produce locomotor stimulation in mice. Eur J Pharmacol. 2009. PubMed
- 6. Gee P, et al. Pharmacology and toxicology of 1,3-dimethylamylamine: a review. Drug Test Anal. 2013. PubMed
- 7. Whitehead PN, et al. Metabolic and thermogenic effects of 1,3-dimethylamylamine in animal models. J Appl Physiol. 2012. (Preclinical metabolic data)
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